Juvenile xanthogranuloma
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ReferencesJuvenile xanthogranuloma (JXG) jẹ́ àìlera tó wọ́pọ̀ àti irú loorekoore ti non‑Langerhans cell histiocytic disorder nínú àwọn ọmọde. Ní to 75 % ti àwọn iṣẹlẹ, àwọn ọ̀gbẹ́ yìí hàn láàrin ọdún àkọ́kọ́ ti ìgbésí ayé, tí 15‑20 % sì ti wá láti ìbímọ̀. Bí ó tilẹ̀ jẹ́ pé ó ṣọ̀wọn nínú àwọn agbalagba, JXG máa ń ṣẹlẹ̀ ní àárín ọdún 20 sí 30, ó sì máa ń ní ọ̀gbẹ́ kan ṣoṣo ní ọ̀pọ̀lọpọ̀ aláìsàn agbalagba. Ní awọ ara, ó farahàn gẹ́gẹ́ bí àwọn ikọlu ofeefee‑osàn‑brown tí ń dúró bí bumps tàbí lumps, pàápàá jùlọ lórí ojú, ọ̀run, àti ara òkè. Àwọn egbo ẹnu kò wọ́pọ̀, ṣùgbọ́n ó lè hàn bí odídì ofeefee ní àgbègbè ahọn tàbí ibòmíràn ní ẹnu, tí ó lè yọrí sí ọ̀gbẹ́ àti ẹ̀jẹ̀. Àwọn egbo awọ ara sábà máa ń jẹ́ aláìlòye, kò sì ní ààmì àìlera, tí ó sì lè wà níbẹ̀ fún ọ̀pọ̀ ọdún. Bí ó tilẹ̀ jẹ́ pé ó ṣọ̀wọn, ilowósi ojú jẹ́ ọ̀ràn tó wọ́pọ̀ jù ilowósi awọ ara lọ, tí ó sì lè tẹ̀síwájú sí ilowósi ẹ̀dọ̀fóró. Ocular JXG máa ń kan ojú kan ṣoṣo, ó sì ń ṣẹlẹ̀ ní kéré ju 0.5 % ti àwọn aláìsàn, bí ó tilẹ̀ jẹ́ pé ní àìmọ̀ 40 % ti àwọn tí ó ní ipa ocular tún ní ọ̀pọ̀ ọ̀gbẹ́ awọ ara nígbà tí a ṣe àyẹ̀wò.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) kì í ṣe wọ́pọ̀; wọ́n jẹ́ àìlera tí ó jẹ́ apá kan nínú ẹ̀ka ńlá ti non‑Langerhans cell histiocytoses. Wọ́n máa hàn gẹ́gẹ́ bí ọ̀kan tàbí ọ̀pọ̀ àwọ̀ pupa tàbí àwọn àkúnya ofeefee, tí a sábà máa rí ní orí tàbí ọ̀run. Ọ̀pọ̀ JXGs ń dásílẹ̀ láti ìbímọ̀ tàbí ní àkókò ọdún kìn‑ín‑ní ìgbésí ayé. Bí ó tilẹ̀ jẹ́ pé wọ́n lè dà bíi àìlera, nígbà míì wọ́n lè ní ipa lórí àwọn apá tó kọjá àwọ̀ ara, pẹ̀lú ìfarapa ojú, èyí tí ó yẹ kí a ṣàyẹ̀wò gẹ́gẹ́ bíi ìtàn àtẹ̀jáde. Ní gbogbogbo, JXG tó wà lórí àwọ̀ ara máa ń lọ́ọ́ kúrò ní ara rẹ̀, ó sì sábà máa kò ní ìtọ́jú.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Ààmì ojú hàn ní tó 10 % àwọn ènìyàn pẹ̀lú JXG, ó sì lè nípa lórí ìran wọn. Bí ó tilẹ̀ jẹ́ pé àwọn ààmì awọ‑ara máa ń parí láìrọ̀rọ̀, àwọn ààmì ojú ṣọ́wọn ní ìlọsíwájú láìrọ̀rọ̀, ó sì nílò ìtọ́jú.